Quinine Sulphate is administered either as monotherapy or with other medications in the treatment of malaria infections,. Quinine Sulphate works by attacking and eliminating the malarial parasites in the red blood cells, Quinine Sulphate causes accumulation of toxic heme pigment, which kills the malarial infection. Quinine Sulphate is widely considered to be effective in areas where chloroquine resistance has been known to occur. Quinine Sulphate can only be used to treat a malaria infection once it has occurred, and it is not safe or effective for preventing malaria.

Patients who take Quinine Sulphate may suffer from such side effects; Nausea, Restlessness, Perspiration, Buzzing noise in the ears Abdominal pain, Blurred vision, Changes in color vision, Dizziness, Face redness, Headache, Altered heart rate, Increased sweating, Ringing in ear, Vertigo, Vomiting.